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Are they safe to use for extended periods

The result, after nearly two decades of development, was exenatide (Byetta) , which received FDA approval in April 2005 as the first GLP-1 receptor agonist approved for clinical use

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Hari L, Brault V, Kleber M, Lee HY, Ille F, Leimeroth R et al

They work by slowing digestion, reducing appetite, and promoting feelings of fullness

The lower aqueous phase (about 26 L) was transferred to the 30 gallon glass-lined steel reactor vessel